Text neck is not associated with neck and upper limb disability in young adults who use smartphones.

PURPOSE: The objective of the present study was to correlate neck and upper-limb disabilities with neck flexion in university students who are smartphone users. While handling smartphones, a posture with sustained neck flexion known as "Text Neck" is usually adopted, and some authors related to musculoskeletal symptoms on the neck and the upper limb. However, recent studies state that such an association is questionable. METHODS: This is an observational study when evaluating 192 university students through questionnaires such as the Neck Disability Index (NDI), Disabilities of Arm, Shoulder, and Hand (DASH), besides the maximal neck flexion, grip and lateral pinch strength of the participants. RESULTS: The sociodemographic questionnaire demonstrated that most participants had used the device for 5 to 10 years, for five or more hours per day. The DASH questionnaire scores presented an average of 7.2 points, while the data regarding grip and lateral pinch strength showed averages of 29.5 kgf and 8.8 kgf, respectively. The NDI questionnaire scores presented an average of 10.5. The average range of motion of the maximum neck flexion was 27°. CONCLUSION: There was no association between neck flexion with the DASH and NDI or the grip and lateral pinch strength after the correlation and binary logistic regression analyses. The results show that the scores of DASH, NDI, hand grip and lateral pinch strength, have no association with the maximum neck flexion.

Socioemotional Factors and Cardiovascular Risk: What Is the Relationship in Brazilian Older Adults?

Background and Objectives: Cardiovascular risk is composed of several modifiable factors that cannot be explained only at the individual level. The aim of this study was to investigate the association between socioemotional factors and cardiovascular risk in older adults. Research Design and Methods: A cross-sectional study with data from The Brazilian Longitudinal Study of Aging (Estudo Longitudinal de Saúde dos Idosos Brasileiros, ELSI-Brazil), population based with data collected between 2015 and 2016. Cardiovascular risk-the study outcome-was assessed using the WHO/ISH Cardiovascular Risk Prediction Charts. The exposure variables were perceived social support from those who would receive help in situations and productive and leisurely social participation carried out in the last 12 months. We used crude and adjusted logistic regression for socioeconomic conditions, health conditions, and lifestyle habits to estimate odds ratio (OR) and 95% confidence intervals (CIs) for the occurrence of the outcome. Results: There were 6,005 participants between 50 and 74 years old with complete data. Of these, 18.7% (95% CI: 16.9-20.6) had high cardiovascular risk. Being in the highest tertile of greater social participation is associated with a lower prevalence of high cardiovascular risk (OR: 0.69; 95% CI: 0.50-0.95), adjusted for all variables, when compared to the lowest tertile. Furthermore, the absence of perceived social support is associated with a higher prevalence in different models. Perceived social support from close family members (son/daughter, son-in-law, and daughter-in-law) for material issues is associated with a higher prevalence, whereas having support from friends for affective resources is associated with a lower prevalence of high cardiovascular risk. Discussion and Implications: Socioemotional factors such as lack of perceived social support and social participation were significantly associated with cardiovascular risk. This suggested that the development of strategies aimed at reducing cardiovascular risk during aging needs to consider socioemotional factors and social relationships.

Is the combination of depression symptoms and multimorbidity associated with the increase of the prevalence of functional disabilities in Brazilian older adults? A cross-sectional study.

Introduction: Functional disabilities are more prevalent in older adults with multimorbidity and depression. However, few studies have investigated the combination of multimorbidity and depression with functional disability. This study aims to verify whether symptoms of depression and multimorbidity combined increase the prevalence of functional disability in Brazilian older adults. Material and methods: This is a cross-sectional study conducted with data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil) baseline examination in 2015-2016 in adults aged 50 years and older. The variables included were basic (BADL) and instrumental activities of daily living (IADL), depressive symptoms, multimorbidity (≥2 chronic diseases), sociodemographic variables, and lifestyle. Logistic regression was performed to estimate crude and adjusted odds ratios. Results: A total of 7,842 participants over 50 years of age were included. Of these, 53.5% were women and 50.5% were between 50 and 59 years old, 33.5% reported ≥4 depressive symptoms, 51.4% had multimorbidity, 13.5% reported difficulty in performing at least one BADL, and 45.1% reported difficulty in performing the IADL. In the adjusted analysis, the prevalence of difficulty on BADL was 6.52 (95% CI: 5.14; 8.27) and on IADL was 2.34 (95% CI: 2.15; 2.55), higher for those with depression and multimorbidity combined when compared with those without these conditions. Conclusion: The combination of symptoms of depression and multimorbidity may increase functional impairments in the BADL and IADL of Brazilian older adults, impairing self-efficacy, independence, and autonomy. Early detection of these factors benefits the person, their family, and the healthcare system for health promotion and disease prevention.

Assessment of knowledge about the neurophysiology of pain and self-perception of skills to assist individuals with pain among undergraduate physiotherapy students in Brazil: cross-sectional study / Avaliação do conhecimento sobre neurofisiologia da dor e autopercepção de habilidades para atender indivíduos com dor em graduandos e graduados em fisioterapia no Brasil: estudo transversal

ABSTRACT BACKGROUND AND OBJECTIVES: Approaches to coping with pain, such as patient education, are directly related to the professionals' skill level. The identification of possible learning gaps in the different stages of training can contribute to the development of new teaching strategies and methods. This study aimed to evaluate and compare the level of knowledge about the neurophysiology of pain and the self-perception of abilities to care for individuals with pain in undergraduate and graduate students in physiotherapy in Brazil. METHODS: This is a cross-sectional analytical observational study, in which the Neurophysiological Pain Questionnaire (QND) was applied to assess the level of knowledge about the neurophysiology of pain. A self-administered questionnaire was also used to collect sociodemographic data from the sample and to assess self-perception of abilities to care for individuals with pain. The characteristics of the study population were defined by descriptive statistics. For the analysis of QND score distribution and self-perception of abilities to care for individuals with pain, the Shapiro-Wilk test was used. In the bivariate analysis to compare the distribution of the QND score and self-perception of abilities to care for individuals with pain between the stages of undergraduates and schooling after graduation, the Kruskal-Wallis test was used, with a significance level of 5% and 95% confidence interval. The statement Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) was used as a guide for reporting the results of the study. RESULTS: A total of 306 volunteers participated in the study, 208 undergraduate students (22.3 ± 3.2 years) and 98 physiotherapists (31.7± 8.7 years). The average QND score for undergraduate students was 6.17 and 8.56 for physiotherapists, considering a total of 12 points. There was a significantly higher difference in the scores obtained on the QND by undergraduates in the intermediate phase and in the last year (p<0.05), as well as in the self-perception of abilities to care for individuals with pain and perform a biopsychosocial approach to the patient, between the different phases of the course. However, among physiotherapists, no significant difference was observed in the total QND score, and in the self-perception of abilities to care for individuals with pain. CONCLUSION: The findings of this study suggest that the level of knowledge about the neurophysiology of pain and self-perception of skills to care for individuals with pain differs between academics and physiotherapy professionals. However, the low QND score of physiotherapy undergraduates, as well as the absence of significant differences in the QND between the different levels of physiotherapist training, suggest that curricular implementation and specific training on pain may be indispensable to increase the level of knowledge and skills of physiotherapists in the treatment of individuals with pain.

RESUMO JUSTIFICATIVA E OBJETIVOS: Abordagens para o enfrentamento da dor, como educação do paciente, estão diretamente relacionadas ao nível de habilidades dos profissionais. A identificação de possíveis lacunas do aprendizado nas diferentes fases de formação pode contribuir para o desenvolvimento de novas estratégias e métodos de ensino. O objetivo deste estudo foi avaliar e comparar o nível de conhecimento sobre neurofisiologia da dor e a autopercepção de habilidades para atender indivíduos com dor em alunos de graduação e graduados em fisioterapia no Brasil. MÉTODOS: Trata-se de um estudo observacional analítico do tipo transversal, em que foi aplicado o Questionário Neurofisiológico de Dor (QND) para avaliar o nível de conhecimento sobre neurofisiologia da dor. Também foi utilizado um questionário autoaplicado para coletar os dados sociodemográficos da amostra e avaliar a autopercepção de habilidades para atender indivíduos com dor. As características da população do estudo foram definidas pela estatística descritiva. Para a análise da distribuição do escore QND e da autopercepção de habilidades para atender indivíduos com dor foi utilizado o teste Shapiro-Wilk. Na análise bivariada para a comparação de distribuição do escore QND e da autopercepção de habilidades para atender indivíduos com dor entre as fases dos graduandos e a escolaridade após a formação foi utilizado o teste de Kruskal-Wallis, nível de significância de 5% e intervalo de confiança de 95%. A declaração Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) foi utilizada como guia para relatar os resultados do estudo. RESULTADOS: Um total de 306 voluntários participaram do estudo, sendo 208 alunos de graduação (22,3 ± 3,2 anos) e 98 fisioterapeutas (31,7± 8,7 anos). A pontuação média do QND para os alunos de graduação foi 6,17 e de 8,56 para os fisioterapeutas, considerando um total de 12 pontos. Observou-se uma diferença significativamente superior na pontuação obtida no QND pelos graduandos da fase intermediária e do último ano (p<0,05), bem como na autopercepção de habilidades para atender indivíduos com dor e realizar uma abordagem biopsicossocial do paciente entre as diferentes fases do curso. Contudo, entre os fisioterapeutas, não foi observada diferença significativa na pontuação total do QND e na autopercepção de habilidades para atender indivíduos com dor. CONCLUSÃO: Por meio dos achados deste estudo, foi possível observar que o nível de conhecimento sobre neurofisiologia da dor e autopercepção de habilidades para atender indivíduos com dor difere entre acadêmicos e profissionais de fisioterapia. Entretanto, a pontuação baixa do QND dos graduandos de fisioterapia, bem como a ausência de diferenças significativas do QND entre os diferentes níveis de formação dos fisioterapeutas, sugere que a implementação curricular e capacitações específicas sobre dor são indispensáveis para ampliar o nível de conhecimento e habilidades dos fisioterapeutas no tratamento de indivíduos com dor.

What is the impact of national public expenditure and its allocation on neonatal and child mortality? A machine learning analysis.

BACKGROUND: Understanding the impact of national public expenditure and its allocation on child mortality may help governments move towards target 3.2 proposed in the 2030 Agenda. The objective of this study was to estimate the impacts of governmental expenditures, total, on health, and on other sectors, on neonatal mortality and mortality of children aged between 28 days and five years. METHODS: This study has an ecological design with a population of 147 countries, with data between 2012 and 2019. Two steps were used: first, the Generalized Propensity Score of public spending was calculated; afterward, the Generalized Propensity Score was used to estimate the expenditures' association with mortality rates. The primary outcomes were neonatal mortality rates (NeoRt) and mortality rates in children between 28 days and 5 years (NeoU5Rt). RESULTS: The 1% variation in Int$ Purchasing Power Parity (Int$ PPP) per capita in total public expenditures, expenditure in health, and in other sectors were associated with a variation of -0.635 (95% CI -1.176, -0.095), -2.17 (95% CI -3.051, -1.289) -0.632 (95% CI -1.169, -0.095) in NeoRt, respectively The same variation in public expenditures in sectors other than health, was associates with a variation of -1.772 (95% CI -6.219, -1.459) on NeoU5Rt. The results regarding the impact of total and health public spending on NeoU5Rt were not consistent. CONCLUSION: Public investments impact mortality in children under 5 years of age. Likely, the allocation of expenditures between the health sector and the other social sectors will have different impacts on mortality between the NeoRt and the NeoU5Rt.

First Thousand Days of Child Life and the Development of Risk Factors for Malocclusions

ABSTRACT Objective: To identify the association between individual and socioeconomic factors during the first thousand days of the child's life and the occurrence of risk behaviors for the development of malocclusions. Material and Methods: Cross-sectional study. A sample of 655 6-year-old schoolchildren and families was included. Interviews with mothers were performed at home. The dependent variables were risk behaviors to the development of malocclusions. Independent variables were socioeconomic conditions, aspects of gestation, birth and health of the child up to two years of age. Bivariate and multivariate analyzes were performed through Poisson regression. Results: Maternal education of less than eight years was independently associated with the interruption of exclusive breastfeeding until the fourth month (PR=1.58 CI 95%; 1.07; 2.37). Occupation of the mother with income [PR=1.26; 1.02; 1.56)], occupation of the father without income [PR=1.46 (1.01; 2.14)] were associated fwith interruption of breastfeeding until the sixth month. Pregnancy in adolescence [PR=0.83 (0.70; 0.98)] and nursery attendance [PR=1.15 (1.02; 1.28)] were associated with bottle use. Nursery attendance [PR=1.27 (1.01; 1.59)], hospitalization in the first 29 days of life [PR=1.34 (1.01; 1.80)], occurrence of reflux [PR=1.30 (1.01; 1.70)] were associated with pacifier using. Conclusion: Variables related to the period of the first thousand days of life are associated with higher risk behaviors for the occurrence of malocclusions.

Doenças cardiovasculares e uso de antipsicóticos na esquizofrenia: uma revisão / Cardiovascular diseases and use of antipsychotics in schizophrenia: a review

RESUMO Objetivo Realizar uma revisão de escopo a respeito dos efeitos adversos cardiovasculares e metabólicos associados ao uso de antipsicóticos em pessoas com o diagnóstico de esquizofrenia. Métodos Foi realizada uma revisão de escopo utilizando-se da base de dados PubMed, com descritores MeSH relacionados às doenças cardiovasculares e antipsicóticos. Foram encontrados 976 artigos, os quais foram filtrados por títulos, seguidos dos resumos e, na sequência, lidos na íntegra. Ao final, foram selecionados 71 artigos para a análise. Resultados O uso de antipsicóticos típicos e atípicos para tratamento da esquizofrenia associa-se a alterações glicêmicas e lipídicas, síndrome metabólica, hipertensão, ganho de peso e morbidade cardiovascular. Os estudos evidenciaram a existência de subdiagnóstico e subtratamento de doenças crônicas nessa população. A mortalidade por doença cardiovascular demonstrou aumento considerável nos pacientes em tratamento com agentes antipsicóticos, em comparação com a população geral. Conclusão Alguns fatores dos antipsicóticos, ainda não completamente determinados na psicofarmacologia, vêm se mostrando relacionados a maior risco de distúrbios metabólicos, comportamentais e intrínsecos às pessoas diagnosticadas com esquizofrenia, os quais podem agravar o curso clínico de tais doenças. Reconhece-se a necessidade de aprimorar o acompanhamento e o diagnóstico de doenças cardiovasculares e metabólicas entre pessoas com diagnóstico de esquizofrenia em tratamento com antipsicóticos típicos e atípicos.

ABSTRACT Objective To perform a scoping review of cardiovascular and metabolic adverse effects associated with the use of antipsychotics in people diagnosed with schizophrenia. Methods A scoping review was conducted based on the PubMed database containing MeSH descriptors related to cardiovascular diseases and antipsychotics. At first moment, 976 articles were found, which were filtered by titles, followed by abstracts, and then fully read. In the end 71 articles were selected for the analysis. Results The use of typical and atypical antipsychotics for the treatment of schizophrenia is associated with glycemic and lipid abnormalities, metabolic syndrome, hypertension, obesity/weight gain, and cardiovascular morbidities. The literature showed underdiagnosis and undertreatment of chronic diseases in this population. Mortality from cardiovascular disease showed a considerable increase in patients under treatment with antipsychotic agents, compared to the general population. Conclusion Factors, still not entirely determined, in the psychopharmacology of antipsychotics have been shown to be related to an increased risk of metabolic, behavioral and intrinsic disorders in people diagnosed with schizophrenia, which may worsen the clinical course of such illnesses. It is recognized that there is a need to improve the monitoring and diagnosis of cardiovascular and metabolic diseases among people diagnosed with schizophrenia on treatment with typical and atypical antipsychotics.

The combined effect of anemia and dynapenia on mortality risk in older adults: 10-Year evidence from the ELSA cohort study.

BACKGROUND/OBJECTIVE: Anemia and dynapenia can occur simultaneously. Separately, both conditions increase the mortality risk with advancing age. However, there is no epidemiological evidence on the combined effect of these conditions on mortality in older adults. We investigated whether combined anemia and dynapenia increase the mortality risk, and whether there are gender differences. METHODS: A 10-year follow-up study was conducted involving 5,310 older adults from the English Longitudinal Study of Ageing (ELSA). According to the diagnosis of anemia (hemoglobin concentration < 13.0 g/dL in men and < 12.0 g/dL in women) and dynapenia (grip strength < 26 kg for men and < 16 kg for women), individuals at baseline were categorized as "non-anemic/non-dynapenic", "dynapenic", "anemic" and "anemic/dynapenic". The outcome was all-cause mortality during the follow-up period. RESULTS: A total of 984 deaths were computed during the follow-up (63.7% in non-anemic/non-dynapenic, 22.8% in dynapenic, 7.5% in anemic and 6.0% in anemic/dynapenic). Adjusted Cox proportional hazard models stratified by sex showed that anemia and dynapenia combined was associated with an increased mortality risk in men (HR: 1.64; 95% IC 1.08 - 2.50) and women (HR: 2.17; 95% CI 1.44 - 3.26). Anemia in men (HR: 1.68; 95% CI 1.22 - 2.32) and dynapenia in women (HR: 1.37; 95% CI 1.09 - 1.72) were also risk factors for mortality. CONCLUSIONS: The coexistence of anemia and dynapenia increases the mortality risk, highlighting the need for early identification, prevention, and treatment of these conditions to reduce their complications and the mortality risk.

The effects of exercise on circulating endocannabinoid levels-a protocol for a systematic review and meta-analysis.

BACKGROUND: Increased circulating endocannabinoids levels are typically associated with aerobic exercise. This phenomenon is associated with a "runner's high," a state of euphoria and well-being experienced after a long exercise. We will provide in this review a transparent and standardized methodology following the PRISMA-P and Cochrane Handbook for Systematic Reviews of Interventions for conducting a systematic review and meta-analysis for synthesizing the available evidence about the effects of physical activity on the circulating levels of AEA and 2-AG endocannabinoids in healthy subjects. METHODS: A multi-disciplinary team with basic and clinical expertise in exercise science developed this protocol. PubMed, EMBASE, Web of Science, CINAHL, SPORTDiscus, and Scopus will be the databases. A health sciences librarian was consulted in the development of the research. Search strategies will combine MeSH terms and free text words, including "exercise," "exercise, physical," "exercise training," "physical activity," "endocannabinoids," "2-arachidonoyl-glycerol," "glyceryl 2-arachidonate," "2-AG," "anandamide," "AEA," "n-arachidonoylethanolamide," "adult," "young adult," and "middle-aged." We will select experimental or quasi-experimental studies published through December 2021. The selection of studies, data extraction, assessment of the risk of bias, and the quality of evidence will be carried out in a paired and independent manner, and the consistency will be assessed using the statistics of Cohen Kappa. Methodological quality will be assessed using the Revised Cochrane risk of bias tool for randomized trials (RoB 2) and the Risk Of Bias In Nonrandomized Studies of Interventions (ROBINS-I) risk tool. We will use the Grading of Recommendations Assessment, Development, and Evaluation to assess the quality of the evidence, χ2 and I2 tests for heterogeneity, funnel plots, and the Egger test for publication bias. A meta-analysis for each data comparison will be performed whenever possible to determine the effect of physical activity on endocannabinoids' circulating levels. DISCUSSION: This systematic review and meta-analysis will provide an overview of the evidence about physical activity over AEA and 2-AG endocannabinoids, including comparability of variables between studies, critical interpretation of results, and use of accurate statistical techniques. The endocannabinoid is molecules by which muscles communicate with other tissues and organs, mediating the beneficial effects of exercise on health and performance, including increased glucose uptake, improved insulin action, and mitochondrial biogenesis. They are essential to exercise. Thus, this study will review the acute effect of physical exercise on circulating levels of endocannabinoids in healthy individuals. The results of this study will potentially be transferred to doctors, health professionals, and legislators to guide their decision making, as well as will improve future research. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020202886 .

Tobacco-related neoplasms: survival analysis and risk of death of population data from Florianópolis, SC.

OBJECTIVE: To estimate the probability of survival and prognostic factors for tobacco-related neoplasms in a population-based cohort. METHODS: This is a cohort with data from the Population-Based Cancer Registry of Florianópolis, southern Brazil, from 2008 to 2012. The Stata 16.0 software was used to estimate the probabilities of survival in five years after diagnosis, by the Kaplan Meier method, and the risk of death, by the Cox regression. RESULTS: A total of 2,829 cancer records related to smoking were included, more prevalent among males, over 70 years of age, nine years or more of schooling, white, with a partner and metastatic diagnosis. The most frequent groupings were colon and rectum (28.7%), trachea, bronchi and lungs (18.6%) and stomach (11.8%). At follow-up, 1,450 died. Pancreatic cancer had the worst probability of survival (14.3%), followed by liver cancer (19.4%). CONCLUSION: Risk factors for death and survival rates differ across the 13 types of tobacco-related cancers. Early diagnosis and primary prevention are strategies that must be improved to improve survival and decrease the burden related to these types of cancer.

Trends in mortality due to traffic accidents in Brazil during the period from 1997 to 2015 for the male population / Tendências da mortalidade em decorrência de traumas de trânsito no Brasil e nas unidades federativas entre os anos de 1997 e 2015 na população masculina

Abstract Background Traffic accidents are one of the main causes of death in Brazil and the increase in the mortality rate is concerning. Objective The study aims to perform a temporal analysis of mortality trends related to traffic accidents in Brazil and its states. Method This is an ecological study of time series of mortality from traffic accidents in Brazil and its Federative Units. Data was obtained from the Information System for Mortality (SIM), processed by Datasus and classified under the headings V01 to V89 (CID-10). Specific mortality rates were calculated and adjusted by age. The temporal tendency analysis was run on the Joinpoint Regression Program. Results The Brazilian male population showed no change in the average annual percentage for the mortality rate (-0.8%; CI 95% -1.7;0.1). Ten states showed increased mortality rates; nine presented a decline, and eight remained constant throughout the period. Conclusion The male population showed no change in the rates, but the mortality rate for the general Brazilian population decreased by 1% per year from 1997 to 2015. Both general and male populations had a decrease of 4.6% and 4.9% per year during the last years, respectively (2012-2015).

Resumo Introdução Acidentes de trânsito são uma das principais causas de morte no Brasil e no mundo. Objetivo O estudo teve por objetivo realizar uma análise temporal da tendência de mortalidade por acidentes de transportes terrestres no Brasil. Método Estudo ecológico de séries temporais da mortalidade por acidentes de transporte terrestre no Brasil no período de 1997 a 2015 para a população masculina. Os dados são provenientes do Sistema de Informação sobre Mortalidade (SIM), processados pelo Datasus e classificados nas rubricas V01 a V89 (CID-10). Foram calculadas as taxas específicas de mortalidade, ajustadas por idade, e realizada análise da tendência temporal através do software Joinpoint Regression Program. Resultados A população brasileira masculina não apresentou mudanças na taxa de mortalidade ao longo dos anos (-0.8%; CI 95% - 1.7;0.1). Dez estados tiveram aumento nas taxas de mortalidade, nove reduziram e oito mantiveram as taxas. Conclusão A população masculina não apresentou diferença nas taxas, entretanto, a população geral apresentou redução de 1% ao ano na taxa mortalidade. Além disso, ambas populações geral e masculina mostraram uma redução de 4,6% e 4,9% ao ano durante os últimos anos (2012- 2015).

Overall survival analyses of female malignancies in Southern Brazil during 2008-2017: A closer look at breast, cervical and ovarian cancer.

Background: The aim of this study was to report the overall survival and baseline factors associated with OS for breast, cervical and ovarian cancer in Florianópolis, Southern Brazil, a region with quality-of-life indicators comparable to high-income countries. Methods: Cohort study was performed from probabilistic record linkage of the Mortality Information System and the Population-based cancer registry of Florianópolis. It was included breasts, cervical and ovarian cancer diagnosis during the period of 2008-2012 with a follow up of 60 months. Cox regression and Kaplan-Meier method were used for associations with overall survival and risk factors. Findings: 1857 cases of the three malignancies were included in the analysis. We identified 202 deaths in breast cancer subjects, 53 for cervical cancer and 51 for ovarian cancer. Metastatic disease at diagnosis was present in 31%, 9.6%, and 55% of the cases, respectively. Overall survival was statistically correlated with age, educational level and stage for breast cancer; age and stage for cervical cancer; age and stage for ovarian cancer. Interpretation: Metastatic disease and age are the main prognostic factors for the malignancies studied, as they were associated with both overall survival and risk of death. Better screening and preventive tests for early diagnosis are needed. Funding: Support of Research and Innovation in the State of Santa Catarina, Research Program for the Unified Health System (FAPESC/MS-DECIT/CNPQ/SES-SC-PPSUS); the Brazilian National Research Council (CNPq); and the Coordination for the Improvement of Higher Education Personnel (CAPES).

Are elevated plasma fibrinogen associated with lung function? An 8-year follow-up of the ELSA study.

BACKGROUND: Fibrinogen is an important biomarker of inflammation, but findings from longitudinal studies that correlated fibrinogen with lung function in older adults are inconsistent. AIM: To investigate the relationship between fibrinogen plasma levels and lung function impairment later in life. METHODS: Longitudinal analysis of 2,150 participants of the English Longitudinal Study of Ageing (ELSA) aged 50 years and older. Associations between changes in plasma fibrinogen between waves 2 (2004-05) and 4 (2008-09) and lung function in wave 6 (2012-13) were performed using multiple linear regression adjusted by potential confounders. RESULTS: Regarding the fibrinogen profile, 18.5% of the participants presented higher levels in both waves. In the adjusted models, the maintenance of high fibrinogen levels was associated with a significant reduction of lung function only for men. FEV1 showed a reduction of 0.17L, FVC of 0.22L, and the percentages predicted were 5.16% for FEV1 and 6.21% for FVC compared to those that maintained normal levels of fibrinogen. DISCUSSION: To the best of our knowledge, this was the first study investigating the relationship between changes in fibrinogen levels over a long follow-up period and lung function in older adults without pre-existing chronic diseases. ELSA has information on critical demographic and clinical parameters, which allowed to adjust for potential confounding factors. CONCLUSION: It was found that the persistence of high levels of plasma fibrinogen in older English men, but not women, is associated with lung function decline. Therefore, plasma fibrinogen showed to be an important biomarker of pulmonary dysfunction in this population.

Análise dos gastos com diagnóstico por imagem no Brasil / Analysis of expenses with diagnostic imaging in Brazil

Resumo Introdução Os gastos em saúde têm sido uma preocupação mundial diante da escassez de recursos financeiros para o atendimento das demandas em saúde. Objetivo Analisar o gasto per capita com diagnóstico por imagem de alta complexidade e associação com variáveis sociodemográficas e estruturais no Brasil. Método Estudo ecológico observacional dos gastos com diagnóstico por imagem utilizando os registros do Sistema de Informação do Sistema Único de Saúde (SUS), com análise de regressão com modelos generalizados de efeitos mistos, de 2008 a 2017, por macrorregiões de saúde, de acordo com as variáveis: PIB per capita, população, taxa de médicos, taxa de equipamentos em uso no SUS e cobertura pela Estratégia Saúde da Família (ESF). Resultados Na análise descritiva dos dados, foi observado aumento dos gastos com diagnóstico por imagem de alta complexidade. Foi identificada correlação positiva entre o gasto e as variáveis taxa de médicos, taxa de equipamentos em uso no SUS e PIB, bem como correlação negativa com a cobertura pela ESF. Conclusão A relação entre ampliação da cobertura pela ESF e diminuição no gasto com diagnóstico por imagem de alta complexidade se apresentou como importante indicador no direcionamento das políticas públicas e de recursos. Assim, macrorregiões com maiores taxas do PIB e de médicos tendem a ter gastos mais elevados com diagnóstico por imagem de alta complexidade.

Abstract Background Health expenditures have become a global concern given the scarcity of financial resources to meet health demands. Objective To analyze the trend of per capita expenditure with high-complexity diagnostic imaging and its association with sociodemographic and structural variables in Brazil. Method Observational, ecological study on diagnostic imaging expenditures using the Unified Health System (SUS) information system records, through regression analysis with Generalized Mixed Effects Models, from 2008 to 2017, by health macro-regions, according to the following variables: GDP per capita, population, rate of physicians, rate of equipment in use at SUS, and coverage by the Family Health Strategy (FHS). Results Descriptive analysis of the data showed an increase in expenses with high-complexity diagnostic imaging. Expenditure was positively correlated with rate of physicians, rate of equipment in use in SUS and GDP per capita, and negatively correlated with FHS coverage. Conclusion The relationship between expansion of coverage by the FHS and decreased expenses with high-complexity diagnostic imaging was an important indicator to direct public policies and allocate resources. Thus, macro-regions with higher GDP per capita and rate of physicians tend to have greater expenses with high-complexity diagnostic imaging.

Complete Tooth Loss and Allostatic Load Changes Later in Life: A 12-Year Follow-Up Analysis of the English Longitudinal Study of Ageing.

OBJECTIVE: There is little evidence of the association between complete tooth loss and allostatic load (AL). We investigated, firstly, the association between complete tooth loss and changes in AL for 12 years among older English adults. A second aim was to explore the role of fruit and vegetable consumption in explaining the aforementioned association. METHODS: AL was calculated for 2430 English Longitudinal Study of Ageing cohort (2004/5-2016/17) participants 50 years and older based on nine biomarkers: systolic and diastolic blood pressures, glycated hemoglobin, high- and low-density lipoprotein cholesterol, triglycerides, fibrinogen, C-reactive protein, and waist circumference. The exposure was complete tooth loss. Participants were classified as dentate or edentulous. A linear mixed-effects model was fitted to model the 12-year change in AL score and its association with complete tooth loss after adjustments for confounders (demographic factors, socioeconomic position, and health behaviors). RESULTS: Around 11% of the participants were edentulous. Complete tooth loss was positively associated with baseline AL scores but not with its rate of change over time. The predicted mean AL scores were 3.60 (95% confidence interval [CI] = 3.53-3.68) and 3.98 (95% CI = 3.76-4.21) as well as 4·28 (95% CI = 4·18, 4·39) and 4·66 (95% CI = 4·42, 4·90) for dentate and edentulous participants, at baseline and end of follow-up, respectively. Fruit and vegetable consumption was not associated with baseline AL or its rate of change. CONCLUSIONS: Complete tooth loss was associated with baseline AL score but not with its development over time, whereas the consumption of fruit and vegetables did not help to explain this association. Both conditions may share common determinants earlier in life.

Aging and dependence in Brazil: sociodemographic and care characteristics of older adults and caregivers. / Envelhecimento e dependência no Brasil: características sociodemográficas e assistenciais de idosos e cuidadores.

This paper aims to identify sociodemographic and care characteristics of dependent older adults, formal and family caregivers in municipalities from different Brazilian regions. A cross-sectional study was carried out with a sample of 175 people, of whom 64 were older adults, 27 formal caregivers, and 84 family caregivers. Semi-structured interviews were conducted with specific questions for each group on the theme of care and dependence. Most older adults were female, aged 80 years or older, with low education and have been dependent for four years or more. Older adults reported feelings of loneliness, pointed out difficulties in medical care, and 29% had only access to Primary Health Care actions. Inequalities, burden, illnesses, and social problems were found among family caregivers. Black females with no formal employment, little or no training for the function, and low remuneration predominated among formal caregivers, and care was associated with domestic chores. We can conclude that gender and race inequalities persist in the care of dependent older adults, and we observed that the rigid social roles assigned to men and women in Brazil persist in the family and work dynamics in caring for the dependent older adults.

O artigo tem como objetivo identificar características sociodemográficas e assistenciais de idosos dependentes, cuidadores formais e familiares em municípios de diferentes regiões brasileiras. Realizou-se um estudo transversal com amostra de 175 pessoas, sendo 64 idosos, 27 cuidadores formais e 84 cuidadores familiares. Foram realizadas entrevistas semiestruturadas, com questões específicas para cada grupo sobre a temática do cuidado e dependência. A maioria dos idosos era do sexo feminino, com idade igual ou maior a 80 anos, com baixa escolaridade e dependente há quatro anos ou mais. Os idosos relataram sentimentos de solidão, apontaram dificuldades na assistência médica e 29% tinham acesso apenas a ações da Atenção Primária à Saúde. Entre os cuidadores familiares, encontrou-se desigualdades, sobrecargas, adoecimentos e problemas sociais. Entre os formais predominou o sexo feminino, a raça negra, sem vínculo legal de trabalho, pouca ou nenhuma formação para a função e baixa remuneração; o cuidado associou-se aos afazeres domésticos. Conclui-se que perduram as desigualdades de gênero e raça no cuidado às pessoas idosas em situação de dependência. Observou-se também que a rigidez dos papeis sociais atribuídos a homens e mulheres no Brasil persistem nas dinâmicas familiares e laborais no cuidado ao idoso dependente.

Envelhecimento e dependência no Brasil: características sociodemográficas e assistenciais de idosos e cuidadores / Aging and dependence in Brazil: sociodemographic and care characteristics of older adults and caregivers

Resumo O artigo tem como objetivo identificar características sociodemográficas e assistenciais de idosos dependentes, cuidadores formais e familiares em municípios de diferentes regiões brasileiras. Realizou-se um estudo transversal com amostra de 175 pessoas, sendo 64 idosos, 27 cuidadores formais e 84 cuidadores familiares. Foram realizadas entrevistas semiestruturadas, com questões específicas para cada grupo sobre a temática do cuidado e dependência. A maioria dos idosos era do sexo feminino, com idade igual ou maior a 80 anos, com baixa escolaridade e dependente há quatro anos ou mais. Os idosos relataram sentimentos de solidão, apontaram dificuldades na assistência médica e 29% tinham acesso apenas a ações da Atenção Primária à Saúde. Entre os cuidadores familiares, encontrou-se desigualdades, sobrecargas, adoecimentos e problemas sociais. Entre os formais predominou o sexo feminino, a raça negra, sem vínculo legal de trabalho, pouca ou nenhuma formação para a função e baixa remuneração; o cuidado associou-se aos afazeres domésticos. Conclui-se que perduram as desigualdades de gênero e raça no cuidado às pessoas idosas em situação de dependência. Observou-se também que a rigidez dos papeis sociais atribuídos a homens e mulheres no Brasil persistem nas dinâmicas familiares e laborais no cuidado ao idoso dependente.

Abstract This paper aims to identify sociodemographic and care characteristics of dependent older adults, formal and family caregivers in municipalities from different Brazilian regions. A cross-sectional study was carried out with a sample of 175 people, of whom 64 were older adults, 27 formal caregivers, and 84 family caregivers. Semi-structured interviews were conducted with specific questions for each group on the theme of care and dependence. Most older adults were female, aged 80 years or older, with low education and have been dependent for four years or more. Older adults reported feelings of loneliness, pointed out difficulties in medical care, and 29% had only access to Primary Health Care actions. Inequalities, burden, illnesses, and social problems were found among family caregivers. Black females with no formal employment, little or no training for the function, and low remuneration predominated among formal caregivers, and care was associated with domestic chores. We can conclude that gender and race inequalities persist in the care of dependent older adults, and we observed that the rigid social roles assigned to men and women in Brazil persist in the family and work dynamics in caring for the dependent older adults.

Racial inequities in tooth loss among older Brazilian adults: A decomposition analysis.

OBJECTIVE: To determine the extent to which racial inequities in tooth loss and functional dentition are explained by individual socioeconomic status, smoking status and frequency/reason for the use of dental services. METHODS: Data came from the Brazilian Longitudinal Study of Ageing, a nationally representative sample of community-dwelling people aged 50 years and over. Tooth loss and functional dentition (ie 20+ natural teeth) were the outcomes. The main explanatory variable was self-classified race. Covariates included dental visits in the past 12 months, dental visits for check-ups only, smoking status, self-reported chronic conditions, depression and cognitive function. Logistic regression and Blinder-Oaxaca decomposition analysis were used to estimate the share of each factor in race-related tooth loss inequities. RESULTS: The analytical sample comprised of 7126 respondents. While the prevalence of functional dentition in White Brazilians was 37% (95% CI: 33.5;40.9), it was 29% (95% CI: 26.4;31.6) among Browns and 30% (95% CI: 25.1;35.4) among Blacks. The average number of lost teeth among Whites, Browns and Blacks were 18.7 (95% CI: 17.8;19.6), 20.4 (95% CI: 19.7;21.1) and 20.8 (95% CI: 19.5;22.0), respectively. Decomposition analysis showed that the selected covariates explained 71% of the racial inequalities in tooth loss. Dental visits in the previous year and smoking status explained nearly half of race-related gaps. Other factors, such as per capita income, education and cognitive status, also had an important contribution to the examined inequalities. The proportion of racial inequities in tooth loss that was explained by dental visits (frequency and reason) and smoking status decreased from 40% for those 50-59 years of age to 22% among participants aged 70-79 years. CONCLUSIONS: Frequency and reason for dental visits and smoking status explained nearly half of the racial inequity in tooth loss among Brazilian older adults. The Brazilian Family Health Strategy Program should target older adults from racial groups living in deprived areas.

Abandono do tratamento e cessação do tabagismo: análise dos dados de um programa de controle / Abandono del tratamiento de la cesación tabáquica: análisis de datos de un programa de control / Abandonment of treatment and smoking cessation: analysis of data from a control program

Objetivo: analisar o perfil dos tabagistas em tratamento e os fatores associados ao abandono do tratamento e cessação do tabagismo em um programa municipal. Método: estudo transversal realizado em Araranguá, Santa Catarina com 109 pessoas do Programa Controle do Tabagismo, entre março e dezembro de 2018. Foram coletadas informações sociodemográficas e de saúde, incluindo sintomas depressivos, impulsividade e capacidade de enfrentamento. Realizou-se análises descritivas e inferenciais. Resultados: 40,4% dos participantes abandonaram o tratamento, grupo que obteve maior média para impulsividade. Os principais motivos relatados para o abandono do tratamento foram: "estar bem sem fumar", situações relacionadas ao trabalho e sintomas de abstinência. Observou-se que 7,64% cessaram o tabagismo e 93,8% apresentavam dependência leve à nicotina. Conclusão: apesar do abandono ser alto, alguns permaneceram em cessação. Os com 49 anos ou menos tiveram abandono significativamente maior e a dependência à nicotina apresenta-se como dificultador significativo da cessação.

Objective: to analyze the profile of smokers undergoing treatment and the factors associated with smoking cessation and smoking cessation in a municipal programo of treatment. Method: cross-sectional study carried out in Araranguá, state of Santa Catarina, with 109 people from the Tobacco Control Program, between March and December of the year 2018. Sociodemographic and health information, including depressive symptoms, impulsivity and coping skills, were collected. Descriptive and inferential analyzes were carried out. Results: 40.4% of the participants abandoned the treatment, group that obtained the highest mean for impulsivity. The main reasons reported for abandoning treatment were: "being well without smoking", work-related situations and withdrawal symptoms. It was observed that 7.64% quit smoking and 93.8% had mild dependence on nicotine. Conclusion: although abandonment is high, some remained in cessation. Those aged 49 years or less were significantly more abandoned and nicotine addiction is a significant impediment to cessation.

Objetivo: analizar el perfil de los tabaquistas en tratamiento y los factores asociados al abandono del tratamiento y cesación del tabaquismo en un programa municipal. Método: estudio transversal realizado en Araranguá, Santa Catarina con 109 personas Programa Controle del Tabaquismo, entre marzo y diciembre de 2018. Fueron colectadas informaciones sociodemográficas y de salud, incluindo síntomas depresivos, impulsividad y capacidad de enfrentamiento. Se realizó análisis descriptivas e inferenciales. Resultados: 40,4% de los participantes abandonaron el tratamiento, grupo que obtuvo mayor media para impulsividad. Los principales motivos relatados para el abandono del tratamiento fueron: "estar bien sin fumar", situaciones relacionadas al trabajo y síntomas de abstinencia. Se observo que 7,64% cesaran el tabaquismo y 93,8% presentaban dependencia leve a la nicotina. Conclusión: a pesar del abandono ser alto, algunos siguieron con la cesación. Los con 49 años o menos tuvieron abandono significativamente mayor y la dependencia a la nicotina se presentaba como dificultador significativo de la cesación.

Prevalence and factors associated with nonspecific low back pain in nursing workers / Prevalencia y factores asociados a la lumbalgia no específica en trabajadores de enfermería / Prevalência e fatores associados à lombalgia inespecífica em trabalhadores de enfermagem

ABSTRACT Objective: to determine the prevalence and factors associated with nonspecific low back pain in nursing workers in a public hospital in the South of the country. Method: a cross-sectional study involving 301 nursing workers. Data collection was carried out from May to October 2017 and, in addition to a questionnaire with sociodemographic, work, health conditions, lifestyle and psychosocial conditions, the Nordic Musculoskeletal Questionnaire was used as a screening tool for low back pain and the Self Report Questionnaire to assess the possibility of minor psychiatric disorders. The Chi-Square test was used to analyze the association between variables, and multivariate analysis with Binary Logistic Regression to estimate the Odds Ratio and the 95% confidence intervals. Results: the prevalence of nonspecific low back pain was 51.4% (95% CI: 45.5-57.3) in the last 12 months and 45.4% (95% CI: 39.4-51.3) in the last seven days, and limitation for activities of daily living and work of 18.1% (95% CI: 13.5-22.7). The presence of other diseases and psychosocial and psychological factors increased the chances of presenting or low back pain discomfort. Conclusion: the results demonstrate the need for greater attention to nursing workers, mainly related to the presence of musculoskeletal pain and to their mental suffering.

RESUMEN Objetivo: determinar la prevalencia y los factores asociados a la lumbalgia no específica en trabajadores de Enfermería de un hospital público del sur del país. Método: estudio transversal en el que participaron 301 trabajadores de Enfermería. La recolección de datos se realizó entre mayo y octubre de 2017 y, además de un cuestionario con datos sociodemográficos, laborales, afecciones de salud, estilo de vida y condiciones psicosociales, se aplicó el Nordic Musculoskeletal Questionnaire como instrumento de rastreo para la lumbalgia y el Self Report Questionnaire para evaluar la posibilidad de trastornos psíquicos menores. Se utilizó la prueba de Chi-Cuadrado para analizar la asociación entre las variables y análisis multivariado con Regresión Logística Binaria para estimar el Odds Ratio y los intervalos de confianza del 95%. Resultados: la prevalencia de la lumbalgia no específica fue del 51,4% (IC95%: 45,5-57,3) en los últimos 12 meses y del 45,4% (IC95%: 39,4-51,3) en los últimos siete días, además de limitación en actividades de la vida diaria e de trabajo del 18,1% (IC95%: 13,5-22,7). La presencia de otras enfermedades y de otros factores psicosociales y psicológicos aumentaron las probabilidades de presentar dolor o malestar lumbar. Conclusión: los resultados demuestran que es necesario prestar mayor atención a los trabajadores de Enfermería, principalmente en relación con la presencia de dolores musculoesqueléticos y con el sufrimiento mental.

RESUMO Objetivo: determinar a prevalência e fatores associados à dor lombar inespecífica em trabalhadores de enfermagem em um hospital público do sul do país. Método: estudo transversal envolvendo 301 trabalhadores de enfermagem. A coleta de dados foi realizada no período de maio a outubro de 2017 e foram aplicados, além de um questionário com dados sociodemográficos, laborais, condições de saúde, estilo de vida e condições psicossociais, o Nordic Musculoskeletal Questionnaire como instrumento de rastreio para dor lombar e o Self Report Questionnaire para avaliação da possibilidade de distúrbios psíquicos menores. Utilizou-se o teste Qui-Quadrado para analisar a associação entre as variáveis e análise multivariável com Regressão Logística Binária para estimar o Odds Ratio e os intervalos de confiança de 95%. Resultados: a prevalência de dor lombar inespecífica foi de 51,4% (IC95%: 45,5-57,3) nos últimos 12 meses e 45,4% (IC95%: 39,4-51,3) nos últimos sete dias e limitação para atividades de vida diária e de trabalho de 18,1% (IC95%: 13,5-22,7). A presença de outras doenças e fatores psicossociais e psicológicos aumentaram as chances de apresentar dor ou desconforto lombar. Conclusão: os resultados demonstram a necessidade de maior atenção aos trabalhadores de enfermagem, principalmente relacionada à presença de dores musculoesqueléticas e ao seu sofrimento mental.